| Primary information |
|---|
| PRRID | PRRID_1249 |
| Ligand Name | dsRNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | Dendritic Cell, B-lymphocyte |
| Domain | cell compartment |
| Sequence of Receptor | Q0PQ88.fasta |
| Swiss prot ID | Q0PQ88 |
| Length Of Receptor | 896 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1249 |
| Ligand Name | dsRNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | Dendritic Cell, B-lymphocyte |
| Domain | cell compartment |
| Sequence of Receptor | Q0PQ88.fasta |
| Swiss prot ID | Q0PQ88 |
| Length Of Receptor | 896 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |