Detailed description page of PRRDB2.0

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PRRID_1230 details
Primary information
PRRIDPRRID_1230
Ligand NameDefensins
SourceHost (Endogenous) (others)
Sequence of ligandMRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
Length68
TypePeptide
OccurenceNatural
Role of LigandDefensins are cationic, microbicidal peptides active against many Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes and mouse skin
Domaincell surface
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionplay a role in UVB induced immune suppression
Assay usedNA
PMID24786223
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1230
Ligand NameDefensins
SourceHost (Endogenous) (others)
Sequence of ligandMRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK
Length68
TypePeptide
OccurenceNatural
Role of LigandDefensins are cationic, microbicidal peptides active against many Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationKeratinocytes and mouse skin
Domaincell surface
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
Functionplay a role in UVB induced immune suppression
Assay usedNA
PMID24786223
Year of Publication2014
Pubchem assayPubchem_assay