Detailed description page of PRRDB2.0
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PRRID_1230 details |
| Primary information | |
|---|---|
| PRRID | PRRID_1230 |
| Ligand Name | Defensins |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK |
| Length | 68 |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | Defensins are cationic, microbicidal peptides active against many Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Keratinocytes and mouse skin |
| Domain | cell surface |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | play a role in UVB induced immune suppression |
| Assay used | NA |
| PMID | 24786223 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information | |
|---|---|
| PRRID | PRRID_1230 |
| Ligand Name | Defensins |
| Source | Host (Endogenous) (others) |
| Sequence of ligand | MRTSYLLLFTLCLLLSEMASGGNFLTGLGHRSDHYNCVSSGGQCLYSACPIFTKIQGTCYRGKAKCCK |
| Length | 68 |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | Defensins are cationic, microbicidal peptides active against many Gram-negative and Gram-positive bacteria, fungi, and enveloped viruses |
| Name of receptor | Toll-like receptor 4 (TLR4) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | Keratinocytes and mouse skin |
| Domain | cell surface |
| Sequence of Receptor | O00206.fasta |
| Swiss prot ID | O00206 |
| Length Of Receptor | 839 |
| Function | play a role in UVB induced immune suppression |
| Assay used | NA |
| PMID | 24786223 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |