Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_1226 details |
| Primary information | |
|---|---|
| PRRID | PRRID_1226 |
| Ligand Name | CpG-ODN |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | improve cell survival, prevent cell apoptosis, attenuate cardiac dysfunction after I/R19, and improve outcome in shock induced by polymicrobial sepsis or trauma hemorrhage |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | C57BL/6 mice |
| Localization | endosomes and endoplasmic reticulum |
| Domain | Intracellular receptors |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | In situ apoptosis assay |
| PMID | 24721797 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information | |
|---|---|
| PRRID | PRRID_1226 |
| Ligand Name | CpG-ODN |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | improve cell survival, prevent cell apoptosis, attenuate cardiac dysfunction after I/R19, and improve outcome in shock induced by polymicrobial sepsis or trauma hemorrhage |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | C57BL/6 mice |
| Localization | endosomes and endoplasmic reticulum |
| Domain | Intracellular receptors |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | In situ apoptosis assay |
| PMID | 24721797 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |