| Primary information |
|---|
| PRRID | PRRID_1222 |
| Ligand Name | CpG-B (ODN2006) |
| Source | Bacteria |
| Sequence of ligand | 5’-tcgtcgttttgtcgttttgtcgtt-3’ |
| Length | 24 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | B-class strongly activate B cells but weakly stimulate IFN-α secretion in pDCs. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs, mast cells |
| Domain | Cell Compartment/Intracellular (Endosome) |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1222 |
| Ligand Name | CpG-B (ODN2006) |
| Source | Bacteria |
| Sequence of ligand | 5’-tcgtcgttttgtcgttttgtcgtt-3’ |
| Length | 24 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | B-class strongly activate B cells but weakly stimulate IFN-α secretion in pDCs. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | pDCs, mast cells |
| Domain | Cell Compartment/Intracellular (Endosome) |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |