| Primary information |
|---|
| PRRID | PRRID_1221 |
| Ligand Name | CpG-A (ODN2216) |
| Source | Bacteria |
| Sequence of ligand | 5’-ggGGGACGA:TCGTCgggggg-3’ |
| Length | 20 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | A-class CpG ODNs activate Toll-like receptor 9 (TLR9), leading to strong immunostimulatory effects. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | mast cells |
| Domain | Cell Compartment/Intracellular (Endosome) |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1221 |
| Ligand Name | CpG-A (ODN2216) |
| Source | Bacteria |
| Sequence of ligand | 5’-ggGGGACGA:TCGTCgggggg-3’ |
| Length | 20 |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | A-class CpG ODNs activate Toll-like receptor 9 (TLR9), leading to strong immunostimulatory effects. |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | mast cells |
| Domain | Cell Compartment/Intracellular (Endosome) |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | TLR9 plays a crucial role in breaking tolerance and developing autoimmunity |
| Assay used | ELISA |
| PMID | 24771328 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |