| Primary information |
|---|
| PRRID | PRRID_1219 |
| Ligand Name | CpG-ODN |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | used to enhance Th1 response, also induces high levels of the anti-inflammatory, Th2- promoting cytokine IL10, which could dampen the resulting Th1 response |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Balb/c mice |
| Localization | Bone marrow derived dendritic cell (BMDC) |
| Domain | NA |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | leads to DC maturation, increased expression of surface co-stimulatory and MHC molecules, and enhanced antigen presentation to naiÃàve T cells |
| Assay used | ELISA |
| PMID | 24720881 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information |
|---|
| PRRID | PRRID_1219 |
| Ligand Name | CpG-ODN |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | used to enhance Th1 response, also induces high levels of the anti-inflammatory, Th2- promoting cytokine IL10, which could dampen the resulting Th1 response |
| Name of receptor | Toll-like receptor 9 (TLR9) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Balb/c mice |
| Localization | Bone marrow derived dendritic cell (BMDC) |
| Domain | NA |
| Sequence of Receptor | Q9NR96.fasta |
| Swiss prot ID | Q9NR96 |
| Length Of Receptor | 1032 |
| Function | leads to DC maturation, increased expression of surface co-stimulatory and MHC molecules, and enhanced antigen presentation to naiÃàve T cells |
| Assay used | ELISA |
| PMID | 24720881 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |