Detailed description page of PRRDB2.0

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PRRID_1217 details
Primary information
PRRIDPRRID_1217
Ligand NameCpG ODN2216
SourceBacteria
Sequence of ligand5’-ggGGGACGA:TCGTCgggggg-3
Length20
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandplays either stimulatory or protective roles in different murine lupus models
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source C57BL/6 inbred mice
LocalizationSplenocytes
Domainintracellular
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionSplenocytes from these mice were found to secrete higher levels of interleukin-10 (IL-10)
Assay usedELISA
PMID24719374
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1217
Ligand NameCpG ODN2216
SourceBacteria
Sequence of ligand5’-ggGGGACGA:TCGTCgggggg-3
Length20
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandplays either stimulatory or protective roles in different murine lupus models
Name of receptorToll-like receptor 9 (TLR9)
Type of receptorToll-like receptor (TLR)
Source C57BL/6 inbred mice
LocalizationSplenocytes
Domainintracellular
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionSplenocytes from these mice were found to secrete higher levels of interleukin-10 (IL-10)
Assay usedELISA
PMID24719374
Year of Publication2014
Pubchem assayPubchem_assay