Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_1210 details |
| Primary information | |
|---|---|
| PRRID | PRRID_1210 |
| Ligand Name | class B CpG DNA motifs |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | act as immuno stimulants |
| Name of receptor | Toll-like receptor 21 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | Macrophages |
| Domain | Cell Compartment/Intracellular (ER compartment) |
| Sequence of Receptor | H9BPA7.fasta |
| Swiss prot ID | H9BPA7 |
| Length Of Receptor | 972 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |
| Primary information | |
|---|---|
| PRRID | PRRID_1210 |
| Ligand Name | class B CpG DNA motifs |
| Source | Bacteria |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Synthetic |
| Role of Ligand | act as immuno stimulants |
| Name of receptor | Toll-like receptor 21 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Chicken |
| Localization | Macrophages |
| Domain | Cell Compartment/Intracellular (ER compartment) |
| Sequence of Receptor | H9BPA7.fasta |
| Swiss prot ID | H9BPA7 |
| Length Of Receptor | 972 |
| Function | TLRs promote cellular activation and the production of cytokines such as interleukin (IL)-12 and interferon (IFN)-c In the case of antigen presenting cells (APCs), TLR stimulation also promotes the up-regulation of major histocompatibility complex class II (MHC-II) and co- stimulatory molecules including CD80 therefore elicitation of a robust adaptive immune response |
| Assay used | ELISA |
| PMID | 24797893 |
| Year of Publication | 2014 |
| Pubchem assay | Pubchem_assay |