Detailed description page of PRRDB2.0

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PRRID_1185 details
Primary information
PRRIDPRRID_1185
Ligand NameViral RNA
SourceBacteria
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorNod-like receptor P3 (NLRP3)
Type of receptorNOD-like receptor (NLR)
Source Human
Localizationplasmacytoid and myeloid DCs
Domainextracellular domain (ECD)
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functioncontrolling antiviral host defense or autoimmune diseases and TLR8 and respond to its activation with TNF production and/or degranulation
Assay usedMicroarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot
PMID24813206
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1185
Ligand NameViral RNA
SourceBacteria
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceNatural
Role of Ligandelicit innate immune response
Name of receptorNod-like receptor P3 (NLRP3)
Type of receptorNOD-like receptor (NLR)
Source Human
Localizationplasmacytoid and myeloid DCs
Domainextracellular domain (ECD)
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functioncontrolling antiviral host defense or autoimmune diseases and TLR8 and respond to its activation with TNF production and/or degranulation
Assay usedMicroarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot
PMID24813206
Year of Publication2014
Pubchem assayPubchem_assay