Detailed description page of PRRDB2.0

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PRRID_1183 details
Primary information
PRRIDPRRID_1183
Ligand Namebacterial and viral nucleic acids containing CpG motifs
SourceBacteria
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandact as immuno stimulants
Name of receptorHSP90
Type of receptorPattern recognition receptor (PRR)
Source Human
Localizationinduces pro-inflammatory cytokine response
DomainCell Compartment/Intracellular (Endosome)
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionTLR9 plays a crucial role in breaking tolerance and developing autoimmunity
Assay usedMicroarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot
PMID24813206
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1183
Ligand Namebacterial and viral nucleic acids containing CpG motifs
SourceBacteria
Sequence of ligandNA
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of Ligandact as immuno stimulants
Name of receptorHSP90
Type of receptorPattern recognition receptor (PRR)
Source Human
Localizationinduces pro-inflammatory cytokine response
DomainCell Compartment/Intracellular (Endosome)
Sequence of ReceptorQ9NR96.fasta
Swiss prot IDQ9NR96
Length Of Receptor1032
FunctionTLR9 plays a crucial role in breaking tolerance and developing autoimmunity
Assay usedMicroarray analysis, Quantitative PCR, Phosphoproteomic screen, Confocal cell imaging,RNA40 pull-down assay and Immunoblot
PMID24813206
Year of Publication2014
Pubchem assayPubchem_assay