Primary information |
---|
PRRID | PRRID_1180 |
Ligand Name | amidation of the mesoDAP |
Source | PGN of Gram-positive bacteria |
Sequence of ligand | C(CC(C(=O)O)N)CC(C(=O)O)N |
Length | NA |
Type | Protein |
Occurence | Natural |
Role of Ligand | activates NOD2 but not recognised by NOD2 |
Name of receptor | Nod-like receptor protein 3 (P2X7R) (NLRP3 (P2X7R) |
Type of receptor | NOD-like receptor (NLR) |
Source | Mice |
Localization | most adult tissues |
Domain | intracellular receptors |
Sequence of Receptor | Q8BHB0.fasta |
Swiss prot ID | Q8BHB0 |
Length Of Receptor | 953 |
Function | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. |
Assay used | NA |
PMID | 24779390 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |
Primary information |
---|
PRRID | PRRID_1180 |
Ligand Name | amidation of the mesoDAP |
Source | PGN of Gram-positive bacteria |
Sequence of ligand | C(CC(C(=O)O)N)CC(C(=O)O)N |
Length | NA |
Type | Protein |
Occurence | Natural |
Role of Ligand | activates NOD2 but not recognised by NOD2 |
Name of receptor | Nod-like receptor protein 3 (P2X7R) (NLRP3 (P2X7R) |
Type of receptor | NOD-like receptor (NLR) |
Source | Mice |
Localization | most adult tissues |
Domain | intracellular receptors |
Sequence of Receptor | Q8BHB0.fasta |
Swiss prot ID | Q8BHB0 |
Length Of Receptor | 953 |
Function | play key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response. |
Assay used | NA |
PMID | 24779390 |
Year of Publication | 2014 |
Pubchem assay | Pubchem_assay |