Detailed description page of PRRDB2.0

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PRRID_1180 details
Primary information
PRRIDPRRID_1180
Ligand Nameamidation of the mesoDAP
SourcePGN of Gram-positive bacteria
Sequence of ligandC(CC(C(=O)O)N)CC(C(=O)O)N
LengthNA
TypeProtein
OccurenceNatural
Role of Ligandactivates NOD2 but not recognised by NOD2
Name of receptor Nod-like receptor protein 3 (P2X7R) (NLRP3 (P2X7R)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationmost adult tissues
Domainintracellular receptors
Sequence of ReceptorQ8BHB0.fasta
Swiss prot IDQ8BHB0
Length Of Receptor953
Functionplay key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response.
Assay usedNA
PMID24779390
Year of Publication2014
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1180
Ligand Nameamidation of the mesoDAP
SourcePGN of Gram-positive bacteria
Sequence of ligandC(CC(C(=O)O)N)CC(C(=O)O)N
LengthNA
TypeProtein
OccurenceNatural
Role of Ligandactivates NOD2 but not recognised by NOD2
Name of receptor Nod-like receptor protein 3 (P2X7R) (NLRP3 (P2X7R)
Type of receptorNOD-like receptor (NLR)
Source Mice
Localizationmost adult tissues
Domainintracellular receptors
Sequence of ReceptorQ8BHB0.fasta
Swiss prot IDQ8BHB0
Length Of Receptor953
Functionplay key roles in regulation of innate immune response. NLRs can cooperate with Toll-like receptors and regulate inflammatory and apoptotic response.
Assay usedNA
PMID24779390
Year of Publication2014
Pubchem assayPubchem_assay