Detailed description page of PRRDB2.0

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PRRID_1133 details
Primary information
PRRIDPRRID_1133
Ligand NameResiquimod (R-848)
Sourceimidazoquinoline (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of Ligandimmune-response modifier possessing antiviral and antitumor activityand also induces the differentiation of MDSCs into mature myeloid cells
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, plasmacytoid DCs and B-lymphocytes
DomainCell Compartment/Intracellular (Endosome)
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
Functionimportant role in the immune response to viral infection
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1133
Ligand NameResiquimod (R-848)
Sourceimidazoquinoline (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of Ligandimmune-response modifier possessing antiviral and antitumor activityand also induces the differentiation of MDSCs into mature myeloid cells
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, plasmacytoid DCs and B-lymphocytes
DomainCell Compartment/Intracellular (Endosome)
Sequence of ReceptorP58681.fasta
Swiss prot IDP58681
Length Of Receptor1050
Functionimportant role in the immune response to viral infection
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay