Detailed description page of PRRDB2.0

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PRRID_1085 details
Primary information
PRRIDPRRID_1085
Ligand NameImiquimod
Sourceimidazoquinoline amine analogue to guanosine (others)
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandAmine analog to guanosine, is an immune response modifier with potent indirect antiviral activity.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functionimportant role in the immune response to viral infection
Assay usedNF-
PMID24098508
Year of Publication2013
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1085
Ligand NameImiquimod
Sourceimidazoquinoline amine analogue to guanosine (others)
Sequence of ligandCC(C)CN1C=NC2=C1C3=CC=CC=C3N=C2N
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandAmine analog to guanosine, is an immune response modifier with potent indirect antiviral activity.
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
Functionimportant role in the immune response to viral infection
Assay usedNF-
PMID24098508
Year of Publication2013
Pubchem assayPubchem_assay