Detailed description page of PRRDB2.0

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PRRID_1084 details
Primary information
PRRIDPRRID_1084
Ligand NameHyaluronan
SourceNA
Sequence of ligandCC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O
LengthNA
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of Ligandthe activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationgraft-versus-host disease (GVHD)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionCD44– hyaluronan contribute to lymphocytotropism to skin GVHD
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1084
Ligand NameHyaluronan
SourceNA
Sequence of ligandCC(=O)NC1CC(C(OC1OC2C(C(C(OC2C(=O)[O-])O)O)O)CO)O
LengthNA
TypeDamage-associated molecular patterns (DAMPs)
OccurenceNatural
Role of Ligandthe activation of TLR4 by hyaluronic acid leads to a different pattern of gene induction
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationgraft-versus-host disease (GVHD)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionCD44– hyaluronan contribute to lymphocytotropism to skin GVHD
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay