Primary information |
---|
PRRID | PRRID_1072 |
Ligand Name | HMGB1 |
Source | Endogenous (others) |
Sequence of ligand | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE |
Length | 215 |
Type | Protein |
Occurence | Natural |
Role of Ligand | play an important role in infectious inflammatory responses. |
Name of receptor | Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), Toll-like receptor 9 (TLR9), RAGE and CD24 |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte |
Domain | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | plays a fundamental role in pathogen recognition and activation of innate immunity |
Assay used | NA |
PMID | 23985302 |
Year of Publication | 2013 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_1072 |
Ligand Name | HMGB1 |
Source | Endogenous (others) |
Sequence of ligand | MGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEEDEEDEEDEEEEEDEEDEDEEEDDDDE |
Length | 215 |
Type | Protein |
Occurence | Natural |
Role of Ligand | play an important role in infectious inflammatory responses. |
Name of receptor | Toll-like receptor 2 (TLR2), Toll-like receptor 4 (TLR4), Toll-like receptor 9 (TLR9), RAGE and CD24 |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | monocyte/macrophages, Myeloid DCs, neutrophils, Mast cells, B-lymphocyte |
Domain | signaling occurs through an adapter protein Toll/IL-1 receptor domain-containing adaptor inducing IFN-b (TRIF) |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | plays a fundamental role in pathogen recognition and activation of innate immunity |
Assay used | NA |
PMID | 23985302 |
Year of Publication | 2013 |
Pubchem assay | NA |