Detailed description page of PRRDB2.0

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PRRID_1068 details
Primary information
PRRIDPRRID_1068
Ligand NameHMGB1
SourceEndogenous (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of Ligandplay an important role in infectious inflammatory responses.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, DCs, B-lymphocytes
Domainextracellular domains of leucine-rich repeat motifs
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1068
Ligand NameHMGB1
SourceEndogenous (others)
Sequence of ligandMGKGDPKKPRGKMSSYAFFVQTCREEHKKKHPDASVNFSEFSKKCSERWKTMSAKEKGKFEDMAKADKARYEREMKTYIPPKGETKKKFKDPNAPKRPPSAFFLFCSEYRPKIKGEHPGLSIGDVAKKLGEMWNNTAADDKQPYEKKAAKLKEKYEKDIAAYRAKGKPDAAKKGVVKAEKSKKKKEEEDDEEDEEDEEEEEEEEDEDEEEDDDDE
Length215
TypeProtein
OccurenceNatural
Role of Ligandplay an important role in infectious inflammatory responses.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
Localizationmonocyte/macrophages, DCs, B-lymphocytes
Domainextracellular domains of leucine-rich repeat motifs
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
Functionsignificant role in the pathogenesis of severe inflammatory responses
Assay usedNA
PMID23985302
Year of Publication2013
Pubchem assayPubchem_assay