Detailed description page of PRRDB2.0

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PRRID_1054 details
Primary information
PRRIDPRRID_1054
Ligand NameH protein
Sourcefimbriae of Escherichia coli (Bacteria)
Sequence of ligandMSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ
Length137
TypeProtein
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationhuman peripheral blood mononuclear cells (hPBMCs)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionTLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system
Assay usedELISA
PMID24016850
Year of Publication2013
Pubchem assayPubchem_assay
Primary information
PRRIDPRRID_1054
Ligand NameH protein
Sourcefimbriae of Escherichia coli (Bacteria)
Sequence of ligandMSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEESAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDENGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ
Length137
TypeProtein
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationhuman peripheral blood mononuclear cells (hPBMCs)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionTLR 4 leads to an intracellular signaling pathway NF-κB and inflammatory cytokine production which is responsible for activating the innate immune system
Assay usedELISA
PMID24016850
Year of Publication2013
Pubchem assayPubchem_assay