Detailed description page of PRRDB2.0

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PRRID_1050 details
Primary information
PRRIDPRRID_1050
Ligand NameFSL-1
Sourcesynthetic lipoprotein (others)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandmimic parts of bacterial lipoproteins
Name of receptorToll-like receptor 6 /2 (TLR6/2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionfundamental role in pathogen recognition and activation of innate immunity.
Assay usedNF-
PMID24098508
Year of Publication2013
Pubchem assayNA
Primary information
PRRIDPRRID_1050
Ligand NameFSL-1
Sourcesynthetic lipoprotein (others)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)OCC(CSC[C@@H](C(=O)NCC(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC2=CN=CN2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](CCCCN)C(=ON[C@@H(COC(=O)N[C@@H](CC4=CC=CC=C4)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC
LengthNA
TypeLipoprotein
OccurenceSynthetic
Role of Ligandmimic parts of bacterial lipoproteins
Name of receptorToll-like receptor 6 /2 (TLR6/2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationHEK293 cells
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionfundamental role in pathogen recognition and activation of innate immunity.
Assay usedNF-
PMID24098508
Year of Publication2013
Pubchem assayNA