Primary information |
---|
PRRID | PRRID_1032 |
Ligand Name | dsRNA |
Source | Virus |
Sequence of ligand | NA |
Length | NA |
Type | Nucleic Acid |
Occurence | Natural |
Role of Ligand | triggers immune responses |
Name of receptor | Toll-like receptor 3 (TLR3) |
Type of receptor | Toll-like receptor (TLR) |
Source | TRIF mutant (C57BL/6J-Ticam1Lps2) mice |
Localization | bone marrow-derived macrophage (BMDM) culture |
Domain | TRIF via a C-terminal RHIM domain interaction with RIP1 or RIP3 |
Sequence of Receptor | Q99MB1.fasta |
Swiss prot ID | Q99MB1 |
Length Of Receptor | 905 |
Function | induce type I interferons (IFN) and other cytokines production. |
Assay used | Quantitative Real Time PCR, Cell Viability Assays, Immunoblot and Immunoprecipitations |
PMID | 24019532 |
Year of Publication | 2013 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_1032 |
Ligand Name | dsRNA |
Source | Virus |
Sequence of ligand | NA |
Length | NA |
Type | Nucleic Acid |
Occurence | Natural |
Role of Ligand | triggers immune responses |
Name of receptor | Toll-like receptor 3 (TLR3) |
Type of receptor | Toll-like receptor (TLR) |
Source | TRIF mutant (C57BL/6J-Ticam1Lps2) mice |
Localization | bone marrow-derived macrophage (BMDM) culture |
Domain | TRIF via a C-terminal RHIM domain interaction with RIP1 or RIP3 |
Sequence of Receptor | Q99MB1.fasta |
Swiss prot ID | Q99MB1 |
Length Of Receptor | 905 |
Function | induce type I interferons (IFN) and other cytokines production. |
Assay used | Quantitative Real Time PCR, Cell Viability Assays, Immunoblot and Immunoprecipitations |
PMID | 24019532 |
Year of Publication | 2013 |
Pubchem assay | Pubchem Assay |