| Primary information |
|---|
| PRRID | PRRID_1032 |
| Ligand Name | dsRNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | TRIF mutant (C57BL/6J-Ticam1Lps2) mice |
| Localization | bone marrow-derived macrophage (BMDM) culture |
| Domain | TRIF via a C-terminal RHIM domain interaction with RIP1 or RIP3 |
| Sequence of Receptor | Q99MB1.fasta |
| Swiss prot ID | Q99MB1 |
| Length Of Receptor | 905 |
| Function | induce type I interferons (IFN) and other cytokines production. |
| Assay used | Quantitative Real Time PCR, Cell Viability Assays, Immunoblot and Immunoprecipitations |
| PMID | 24019532 |
| Year of Publication | 2013 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_1032 |
| Ligand Name | dsRNA |
| Source | Virus |
| Sequence of ligand | NA |
| Length | NA |
| Type | Nucleic Acid |
| Occurence | Natural |
| Role of Ligand | triggers immune responses |
| Name of receptor | Toll-like receptor 3 (TLR3) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | TRIF mutant (C57BL/6J-Ticam1Lps2) mice |
| Localization | bone marrow-derived macrophage (BMDM) culture |
| Domain | TRIF via a C-terminal RHIM domain interaction with RIP1 or RIP3 |
| Sequence of Receptor | Q99MB1.fasta |
| Swiss prot ID | Q99MB1 |
| Length Of Receptor | 905 |
| Function | induce type I interferons (IFN) and other cytokines production. |
| Assay used | Quantitative Real Time PCR, Cell Viability Assays, Immunoblot and Immunoprecipitations |
| PMID | 24019532 |
| Year of Publication | 2013 |
| Pubchem assay | Pubchem Assay |