Detailed description page of PRRDB2.0

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PRRID_1012 details
Primary information
PRRIDPRRID_1012
Ligand NameResquimod
Source3M Pharma (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
Typeimidazoquinolines
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 7/8 (TLR7/8)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionRecognition of extracellular PAMPs Activation leads to pro-inflammatory cytokines and type I IFNs production Set the pace for an adaptive immune response via T and B cells.
Assay usedNA
PMID23017246
Year of Publication2012
Pubchem assayNA
Primary information
PRRIDPRRID_1012
Ligand NameResquimod
Source3M Pharma (others)
Sequence of ligandCCOCC1=NC2=C(N1CC(C)(C)O)C3=CC=CC=C3N=C2N
LengthNA
Typeimidazoquinolines
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 7/8 (TLR7/8)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionRecognition of extracellular PAMPs Activation leads to pro-inflammatory cytokines and type I IFNs production Set the pace for an adaptive immune response via T and B cells.
Assay usedNA
PMID23017246
Year of Publication2012
Pubchem assayNA