Detailed description page of PRRDB2.0

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PRRID_0976 details
Primary information
PRRIDPRRID_0976
Ligand NameANA773
SourceAnadys Pharmaceuticals (others)
Sequence of ligandNA
LengthNA
Typeprodrug of isatoribine
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
FunctionRecognition of extracellular PAMPs Activation leads to pro-inflammatory cytokines and type I IFNs production Set the pace for an adaptive immune response via T and B cells.
Assay usedNA
PMID23017246
Year of Publication2012
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0976
Ligand NameANA773
SourceAnadys Pharmaceuticals (others)
Sequence of ligandNA
LengthNA
Typeprodrug of isatoribine
OccurenceSynthetic
Role of LigandImmunostimulant
Name of receptorToll-like receptor 7 (TLR7)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9NYK1.fasta
Swiss prot IDQ9NYK1
Length Of Receptor1049
FunctionRecognition of extracellular PAMPs Activation leads to pro-inflammatory cytokines and type I IFNs production Set the pace for an adaptive immune response via T and B cells.
Assay usedNA
PMID23017246
Year of Publication2012
Pubchem assayPubchem Assay