| Primary information |
|---|
| PRRID | PRRID_0943 |
| Ligand Name | Pam2CSK4 |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OCC(CSCC(C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC |
| Length | NA |
| Type | diacylated lipopeptide |
| Occurence | Synthetic |
| Role of Ligand | Bacterial lipoproteins are strong immune modulators that activate early innate host responses after infection |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | NA |
| Domain | Intracellular TIR domains |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | fundamental role in pathogen recognition and activation of innate immunity |
| Assay used | NA |
| PMID | 21959264 |
| Year of Publication | 2011 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0943 |
| Ligand Name | Pam2CSK4 |
| Source | NA |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)OCC(CSCC(C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O)N)OC(=O)CCCCCCCCCCCCCCC |
| Length | NA |
| Type | diacylated lipopeptide |
| Occurence | Synthetic |
| Role of Ligand | Bacterial lipoproteins are strong immune modulators that activate early innate host responses after infection |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | NA |
| Domain | Intracellular TIR domains |
| Sequence of Receptor | O60603.fasta |
| Swiss prot ID | O60603 |
| Length Of Receptor | 784 |
| Function | fundamental role in pathogen recognition and activation of innate immunity |
| Assay used | NA |
| PMID | 21959264 |
| Year of Publication | 2011 |
| Pubchem assay | Pubchem Assay |