Detailed description page of PRRDB2.0

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PRRID_0914 details
Primary information
PRRIDPRRID_0914
Ligand NameImidazoquinoline
SourceA tricyclic aromatic heterocycle formed by fusion of an imidazole ring with the pyridine ring
Sequence of ligandCC1=C(NC(=C(C1=C2C=CC(=C(C2=O)OC)OC)N)C3=NC4=C(C=C3)C(=O)C(=C5C4=NC(N5)(C)C)OC)C(=O)O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandImidazoquinolines are being actively being pursued for therapeutic use anti-viral and anti- allergic
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionimportant role in the immune response to viral infection
Assay usedNA
PMID21955443
Year of Publication2011
Pubchem assayNA
Primary information
PRRIDPRRID_0914
Ligand NameImidazoquinoline
SourceA tricyclic aromatic heterocycle formed by fusion of an imidazole ring with the pyridine ring
Sequence of ligandCC1=C(NC(=C(C1=C2C=CC(=C(C2=O)OC)OC)N)C3=NC4=C(C=C3)C(=O)C(=C5C4=NC(N5)(C)C)OC)C(=O)O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandImidazoquinolines are being actively being pursued for therapeutic use anti-viral and anti- allergic
Name of receptorToll-like receptor 8 (TLR8)
Type of receptorToll-like receptor (TLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
Functionimportant role in the immune response to viral infection
Assay usedNA
PMID21955443
Year of Publication2011
Pubchem assayNA