| Primary information |
|---|
| PRRID | PRRID_0868 |
| Ligand Name | alum (aluminium adjuvants ) |
| Source | NA |
| Sequence of ligand | O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+] |
| Length | NA |
| Type | NA |
| Occurence | Synthetic |
| Role of Ligand | NA |
| Name of receptor | Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing3 (Nalp3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Eosinophils |
| Domain | NA |
| Sequence of Receptor | Q96P20.fasta |
| Swiss prot ID | Q96P20 |
| Length Of Receptor | 1036 |
| Function | NLRP3 responds to microbial products and host-derived danger signals and activates the caspase-1- dependent inflammasome |
| Assay used | real-time reverse transcription-PCR, FACS, ELISA |
| PMID | 21978001 |
| Year of Publication | 2011 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0868 |
| Ligand Name | alum (aluminium adjuvants ) |
| Source | NA |
| Sequence of ligand | O.O.O.O.O.O.O.O.O.O.O.O.[O-]S(=O)(=O)[O-].[O-]S(=O)(=O)[O-].[Al+3].[K+] |
| Length | NA |
| Type | NA |
| Occurence | Synthetic |
| Role of Ligand | NA |
| Name of receptor | Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing3 (Nalp3) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | Human |
| Localization | Eosinophils |
| Domain | NA |
| Sequence of Receptor | Q96P20.fasta |
| Swiss prot ID | Q96P20 |
| Length Of Receptor | 1036 |
| Function | NLRP3 responds to microbial products and host-derived danger signals and activates the caspase-1- dependent inflammasome |
| Assay used | real-time reverse transcription-PCR, FACS, ELISA |
| PMID | 21978001 |
| Year of Publication | 2011 |
| Pubchem assay | Pubchem Assay |