Primary information |
---|
PRRID | PRRID_0866 |
Ligand Name | β2-Glycoprotein I (β2-gpI) |
Source | Human (others) |
Sequence of ligand | NA |
Length | NA |
Type | Glycoprotein |
Occurence | Natural |
Role of Ligand | It triggers the downstream phosphorylation of kinases and activation of NF- |
Name of receptor | Toll-like receptor 2 (TLR2) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Endothelial cells |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O60603.fasta |
Swiss prot ID | O60603 |
Length Of Receptor | 784 |
Function | It recruits the MyD88 adapter protein and lead to the production of proinflammatory cytokines |
Assay used | Reporter gene assay |
PMID | 20601596 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0866 |
Ligand Name | β2-Glycoprotein I (β2-gpI) |
Source | Human (others) |
Sequence of ligand | NA |
Length | NA |
Type | Glycoprotein |
Occurence | Natural |
Role of Ligand | It triggers the downstream phosphorylation of kinases and activation of NF- |
Name of receptor | Toll-like receptor 2 (TLR2) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Endothelial cells |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O60603.fasta |
Swiss prot ID | O60603 |
Length Of Receptor | 784 |
Function | It recruits the MyD88 adapter protein and lead to the production of proinflammatory cytokines |
Assay used | Reporter gene assay |
PMID | 20601596 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |