Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0866 details
Primary information
PRRIDPRRID_0866
Ligand Nameβ2-Glycoprotein I (β2-gpI)
SourceHuman (others)
Sequence of ligandNA
LengthNA
TypeGlycoprotein
OccurenceNatural
Role of LigandIt triggers the downstream phosphorylation of kinases and activation of NF-
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationEndothelial cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt recruits the MyD88 adapter protein and lead to the production of proinflammatory cytokines
Assay usedReporter gene assay
PMID20601596
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0866
Ligand Nameβ2-Glycoprotein I (β2-gpI)
SourceHuman (others)
Sequence of ligandNA
LengthNA
TypeGlycoprotein
OccurenceNatural
Role of LigandIt triggers the downstream phosphorylation of kinases and activation of NF-
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationEndothelial cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt recruits the MyD88 adapter protein and lead to the production of proinflammatory cytokines
Assay usedReporter gene assay
PMID20601596
Year of Publication2010
Pubchem assayPubchem Assay