Detailed description page of PRRDB2.0
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PRRID_0850 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0850 |
| Ligand Name | Zymosan |
| Source | gram-positive bacteria and yeast |
| Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O |
| Length | NA |
| Type | Glucan |
| Occurence | Natural |
| Role of Ligand | Their bindng leads to the secretion of the proinflammatory cytokines through NF-KB pathways |
| Name of receptor | Toll-like receptor 2/6 (TLR2/6) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | cerebral endothelial cell line hCMEC/D3 |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It's activation causes tight junction disruption in CECs |
| Assay used | NA |
| PMID | 20637248 |
| Year of Publication | 2010 |
| Pubchem assay | NA |
| Primary information | |
|---|---|
| PRRID | PRRID_0850 |
| Ligand Name | Zymosan |
| Source | gram-positive bacteria and yeast |
| Sequence of ligand | C(C1C(C(C(C(O1)O)O)O)O)O |
| Length | NA |
| Type | Glucan |
| Occurence | Natural |
| Role of Ligand | Their bindng leads to the secretion of the proinflammatory cytokines through NF-KB pathways |
| Name of receptor | Toll-like receptor 2/6 (TLR2/6) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Human |
| Localization | cerebral endothelial cell line hCMEC/D3 |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | NA |
| Swiss prot ID | NA |
| Length Of Receptor | NA |
| Function | It's activation causes tight junction disruption in CECs |
| Assay used | NA |
| PMID | 20637248 |
| Year of Publication | 2010 |
| Pubchem assay | NA |