| Primary information |
|---|
| PRRID | PRRID_0775 |
| Ligand Name | Pore-forming toxins |
| Source | Listeria monocytogenes, Staphylococcus aureus, Aeromonas hydrophila, microbial toxins (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | Activates Caspase-1, which results in the processing and release of the proinfl ammatory cytokines IL-1β and IL-18, leads to pathogen clearance and sepsis resistance. |
| Name of receptor | Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containin (NALP) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | Q9C000.fasta |
| Swiss prot ID | Q9C000 |
| Length Of Receptor | 1473 |
| Function | It results into pathogen clearance and sepsis resistance |
| Assay used | NA |
| PMID | 20740341 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0775 |
| Ligand Name | Pore-forming toxins |
| Source | Listeria monocytogenes, Staphylococcus aureus, Aeromonas hydrophila, microbial toxins (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | Activates Caspase-1, which results in the processing and release of the proinfl ammatory cytokines IL-1β and IL-18, leads to pathogen clearance and sepsis resistance. |
| Name of receptor | Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containin (NALP) |
| Type of receptor | NOD-like receptor (NLR) |
| Source | |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | Q9C000.fasta |
| Swiss prot ID | Q9C000 |
| Length Of Receptor | 1473 |
| Function | It results into pathogen clearance and sepsis resistance |
| Assay used | NA |
| PMID | 20740341 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |