Detailed description page of PRRDB2.0

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PRRID_0761 details
Primary information
PRRIDPRRID_0761
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt results into the induction of type I IFNs
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Chicken
LocalizationSpleenocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorD6R3C9.fasta
Swiss prot IDD6R3C9
Length Of Receptor66
FunctionImmunostimulation
Assay usedNA
PMID20692289
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0761
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandIt results into the induction of type I IFNs
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source Chicken
LocalizationSpleenocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorD6R3C9.fasta
Swiss prot IDD6R3C9
Length Of Receptor66
FunctionImmunostimulation
Assay usedNA
PMID20692289
Year of Publication2010
Pubchem assayPubchem Assay