Detailed description page of PRRDB2.0

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PRRID_0759 details
Primary information
PRRIDPRRID_0759
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandNA
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source CNS
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt causes neurodegeneration
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayNA
Primary information
PRRIDPRRID_0759
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandNA
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source CNS
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt causes neurodegeneration
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayNA