Detailed description page of PRRDB2.0

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PRRID_0754 details
Primary information
PRRIDPRRID_0754
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandSecretion of proinflammatory cytokines such as TFG-β and IL-6
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source DF-MSCs & DP-MSCs
LocalizationTooth
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20731536
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0754
Ligand Namepolyinosinic-polycytidylic acid [poly(I:C)]
SourceNA
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypeNucleic Acid
OccurenceSynthetic
Role of LigandSecretion of proinflammatory cytokines such as TFG-β and IL-6
Name of receptorToll-like receptor 3 (TLR3)
Type of receptorToll-like receptor (TLR)
Source DF-MSCs & DP-MSCs
LocalizationTooth
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO15455.fasta
Swiss prot IDO15455
Length Of Receptor904
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20731536
Year of Publication2010
Pubchem assayPubchem Assay