Detailed description page of PRRDB2.0

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PRRID_0742 details
Primary information
PRRIDPRRID_0742
Ligand NamePam3Cys
SourceB. burgdorferi(Bacteria)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypePeptidoglycan
OccurenceSynthetic
Role of LigandInduction of protective immunity correlated with the development of Abs against an epitope on the C-terminus of OspA
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationdendritic cells, macrophages and lymphocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0742
Ligand NamePam3Cys
SourceB. burgdorferi(Bacteria)
Sequence of ligandCCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O
LengthNA
TypePeptidoglycan
OccurenceSynthetic
Role of LigandInduction of protective immunity correlated with the development of Abs against an epitope on the C-terminus of OspA
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
Localizationdendritic cells, macrophages and lymphocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay