Detailed description page of PRRDB2.0

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PRRID_0740 details
Primary information
PRRIDPRRID_0740
Ligand NamePeptidoglycan (PGN)
SourceGram-negative bacteria
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceSynthetic
Role of LigandIt mediates the effect through a TLR2/PI3K/Aktdependent mechanism.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationHeart
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt induces induce cardioprotection against ischaemia/reperfusion injury
Assay usedEMSA
PMID20421349
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0740
Ligand NamePeptidoglycan (PGN)
SourceGram-negative bacteria
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceSynthetic
Role of LigandIt mediates the effect through a TLR2/PI3K/Aktdependent mechanism.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationHeart
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt induces induce cardioprotection against ischaemia/reperfusion injury
Assay usedEMSA
PMID20421349
Year of Publication2010
Pubchem assayPubchem Assay