Detailed description page of PRRDB2.0

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PRRID_0729 details
Primary information
PRRIDPRRID_0729
Ligand NamePeptidoglycan (PGN)
SourceEscherichia coli, Chlamydia pneumoniae, Campylobacter jejuni, Salmonella typhimurium, Pseudomonas ae
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of LigandActivates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance
Name of receptorNucleotide Binding Oligomerization Domain Containing 1 (Nod1)
Type of receptorNOD-like receptor (NLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9Y239.fasta
Swiss prot IDQ9Y239
Length Of Receptor953
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0729
Ligand NamePeptidoglycan (PGN)
SourceEscherichia coli, Chlamydia pneumoniae, Campylobacter jejuni, Salmonella typhimurium, Pseudomonas ae
Sequence of ligandCC(C(=O)O)OC1C(C(OC(C1O)CO)O)N
LengthNA
TypePeptidoglycan
OccurenceNatural
Role of LigandActivates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance
Name of receptorNucleotide Binding Oligomerization Domain Containing 1 (Nod1)
Type of receptorNOD-like receptor (NLR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9Y239.fasta
Swiss prot IDQ9Y239
Length Of Receptor953
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay