| Primary information |
|---|
| PRRID | PRRID_0724 |
| Ligand Name | Pam3CSK4 |
| Source | Bacteria |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O |
| Length | NA |
| Type | Lipopeptides |
| Occurence | Synthetic |
| Role of Ligand | It mediates the effect through a TLR2/PI3K/Aktdependent mechanism. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Heart |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | It induces induce cardioprotection against ischaemia/reperfusion injury |
| Assay used | EMSA |
| PMID | 20421349 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0724 |
| Ligand Name | Pam3CSK4 |
| Source | Bacteria |
| Sequence of ligand | CCCCCCCCCCCCCCCC(=O)NC(CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)O |
| Length | NA |
| Type | Lipopeptides |
| Occurence | Synthetic |
| Role of Ligand | It mediates the effect through a TLR2/PI3K/Aktdependent mechanism. |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Heart |
| Domain | Leucine-rich Repeat (LRR) Domain |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | It induces induce cardioprotection against ischaemia/reperfusion injury |
| Assay used | EMSA |
| PMID | 20421349 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |