Detailed description page of PRRDB2.0

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PRRID_0720 details
Primary information
PRRIDPRRID_0720
Ligand NamePaclitaxel
SourceNA
Sequence of ligandC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
LengthNA
TypeDrug
OccurenceSynthetic
Role of LigandIt hasthe role in the activation of the adapter protein MyD88 was linked to reduction of apoptosis in cancer cells.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human(Ovarian Cancer Patient)
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionNA
Assay usedNA
PMID20728343
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0720
Ligand NamePaclitaxel
SourceNA
Sequence of ligandC1=C2C(C(=O)C3(C(CC4C(C3C(C(C2(C)C)(CC1OC(=O)C(C(C5=CC=CC=C5)NC(=O)C6=CC=CC=C6)O)O)OC(=O)C7=CC=CC=C7)(CO4)OC(=O)C)O)C)OC(=O)C
LengthNA
TypeDrug
OccurenceSynthetic
Role of LigandIt hasthe role in the activation of the adapter protein MyD88 was linked to reduction of apoptosis in cancer cells.
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human(Ovarian Cancer Patient)
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionNA
Assay usedNA
PMID20728343
Year of Publication2010
Pubchem assayPubchem Assay