Detailed description page of PRRDB2.0

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PRRID_0694 details
Primary information
PRRIDPRRID_0694
Ligand Namemuramyl dipeptide (MDP) + LPS + Poly(I:C)
SourceBacteria
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypePeptide
OccurenceNatural
Role of LigandIt help in NF
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source C57BL/6 Mice
Localizationliver and Hepatocytes
DomainNA
Sequence of ReceptorQ3UP24.fasta
Swiss prot IDQ3UP24
Length Of Receptor1024
FunctionIt plays an important regulatory role in many inflammatory processes involving the liver.
Assay usedImmunoblotting and EMSA
PMID20615568
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0694
Ligand Namemuramyl dipeptide (MDP) + LPS + Poly(I:C)
SourceBacteria
Sequence of ligandC1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O
LengthNA
TypePeptide
OccurenceNatural
Role of LigandIt help in NF
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source C57BL/6 Mice
Localizationliver and Hepatocytes
DomainNA
Sequence of ReceptorQ3UP24.fasta
Swiss prot IDQ3UP24
Length Of Receptor1024
FunctionIt plays an important regulatory role in many inflammatory processes involving the liver.
Assay usedImmunoblotting and EMSA
PMID20615568
Year of Publication2010
Pubchem assayPubchem Assay