Primary information |
---|
PRRID | PRRID_0693 |
Ligand Name | muramyl dipeptide (MDP) |
Source | Bacteria |
Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
Length | NA |
Type | Peptide |
Occurence | Natural |
Role of Ligand | upon ligand sensing, oligomerize and recruit RIP2 via CARD-CARD interactions |
Name of receptor | Nod-like receptor C4 (NLRC4) |
Type of receptor | NOD-like receptor (NLR) |
Source | NA |
Localization | NA |
Domain | NA |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | It culminates in the activation of the NF-kB transcription factor, which drives proinflammatory gene regulation |
Assay used | NA |
PMID | 20303873 |
Year of Publication | 2010 |
Pubchem assay | NA |
Primary information |
---|
PRRID | PRRID_0693 |
Ligand Name | muramyl dipeptide (MDP) |
Source | Bacteria |
Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
Length | NA |
Type | Peptide |
Occurence | Natural |
Role of Ligand | upon ligand sensing, oligomerize and recruit RIP2 via CARD-CARD interactions |
Name of receptor | Nod-like receptor C4 (NLRC4) |
Type of receptor | NOD-like receptor (NLR) |
Source | NA |
Localization | NA |
Domain | NA |
Sequence of Receptor | NA |
Swiss prot ID | NA |
Length Of Receptor | NA |
Function | It culminates in the activation of the NF-kB transcription factor, which drives proinflammatory gene regulation |
Assay used | NA |
PMID | 20303873 |
Year of Publication | 2010 |
Pubchem assay | NA |