Detailed description page of PRRDB2.0

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PRRID_0693 details
Primary information
PRRIDPRRID_0693
Ligand Namemuramyl dipeptide (MDP)
SourceBacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of Ligandupon ligand sensing, oligomerize and recruit RIP2 via CARD-CARD interactions
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt culminates in the activation of the NF-kB transcription factor, which drives proinflammatory gene regulation
Assay usedNA
PMID20303873
Year of Publication2010
Pubchem assayNA
Primary information
PRRIDPRRID_0693
Ligand Namemuramyl dipeptide (MDP)
SourceBacteria
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of Ligandupon ligand sensing, oligomerize and recruit RIP2 via CARD-CARD interactions
Name of receptorNod-like receptor C4 (NLRC4)
Type of receptorNOD-like receptor (NLR)
Source NA
LocalizationNA
DomainNA
Sequence of ReceptorNA
Swiss prot IDNA
Length Of ReceptorNA
FunctionIt culminates in the activation of the NF-kB transcription factor, which drives proinflammatory gene regulation
Assay usedNA
PMID20303873
Year of Publication2010
Pubchem assayNA