Detailed description page of PRRDB2.0

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PRRID_0692 details
Primary information
PRRIDPRRID_0692
Ligand Namemuramyl dipeptide (MDP)
SourceStreptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria)
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of LigandActivates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance
Name of receptorcluster of differentiation 14 (CD14)
Type of receptorPattern recognition receptor (PRR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9HC29.fasta
Swiss prot IDQ9HC29
Length Of Receptor1040
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0692
Ligand Namemuramyl dipeptide (MDP)
SourceStreptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria)
Sequence of ligandCC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C
LengthNA
TypePeptide
OccurenceNatural
Role of LigandActivates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance
Name of receptorcluster of differentiation 14 (CD14)
Type of receptorPattern recognition receptor (PRR)
Source Human
LocalizationNA
DomainNA
Sequence of ReceptorQ9HC29.fasta
Swiss prot IDQ9HC29
Length Of Receptor1040
FunctionIt results into pathogen clearance and sepsis resistance
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay