Primary information |
---|
PRRID | PRRID_0692 |
Ligand Name | muramyl dipeptide (MDP) |
Source | Streptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria) |
Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
Length | NA |
Type | Peptide |
Occurence | Natural |
Role of Ligand | Activates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance |
Name of receptor | cluster of differentiation 14 (CD14) |
Type of receptor | Pattern recognition receptor (PRR) |
Source | Human |
Localization | NA |
Domain | NA |
Sequence of Receptor | Q9HC29.fasta |
Swiss prot ID | Q9HC29 |
Length Of Receptor | 1040 |
Function | It results into pathogen clearance and sepsis resistance |
Assay used | NA |
PMID | 20740341 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0692 |
Ligand Name | muramyl dipeptide (MDP) |
Source | Streptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria) |
Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
Length | NA |
Type | Peptide |
Occurence | Natural |
Role of Ligand | Activates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance |
Name of receptor | cluster of differentiation 14 (CD14) |
Type of receptor | Pattern recognition receptor (PRR) |
Source | Human |
Localization | NA |
Domain | NA |
Sequence of Receptor | Q9HC29.fasta |
Swiss prot ID | Q9HC29 |
Length Of Receptor | 1040 |
Function | It results into pathogen clearance and sepsis resistance |
Assay used | NA |
PMID | 20740341 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |