| Primary information |
|---|
| PRRID | PRRID_0692 |
| Ligand Name | muramyl dipeptide (MDP) |
| Source | Streptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria) |
| Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
| Length | NA |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | Activates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance |
| Name of receptor | cluster of differentiation 14 (CD14) |
| Type of receptor | Pattern recognition receptor (PRR) |
| Source | Human |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | Q9HC29.fasta |
| Swiss prot ID | Q9HC29 |
| Length Of Receptor | 1040 |
| Function | It results into pathogen clearance and sepsis resistance |
| Assay used | NA |
| PMID | 20740341 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information |
|---|
| PRRID | PRRID_0692 |
| Ligand Name | muramyl dipeptide (MDP) |
| Source | Streptococcus pneumoniae, Mycobacterium tuberculosis, and Listeria monocytogenes (Bacteria) |
| Sequence of ligand | CC(C(=O)NC(CCC(=O)O)C(=O)N)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C |
| Length | NA |
| Type | Peptide |
| Occurence | Natural |
| Role of Ligand | Activates NF-KB which results in the processing and release of the proinfl ammatory cytokines IL-1β, which results into pathogen clearance and sepsis resistance |
| Name of receptor | cluster of differentiation 14 (CD14) |
| Type of receptor | Pattern recognition receptor (PRR) |
| Source | Human |
| Localization | NA |
| Domain | NA |
| Sequence of Receptor | Q9HC29.fasta |
| Swiss prot ID | Q9HC29 |
| Length Of Receptor | 1040 |
| Function | It results into pathogen clearance and sepsis resistance |
| Assay used | NA |
| PMID | 20740341 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |