Detailed description page of PRRDB2.0

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PRRID_0687 details
Primary information
PRRIDPRRID_0687
Ligand NameMPLA
SourceSalmonella minnesota R595 (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1O)COC2C(C(C(C(O2)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandNA
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Dogs
Localizationdendritic cells and macrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorF1PDB9.fasta
Swiss prot IDF1PDB9
Length Of Receptor833
Function1,000-fold less toxic than LPS and can be used as vaccines
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0687
Ligand NameMPLA
SourceSalmonella minnesota R595 (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)NC1C(C(C(OC1O)COC2C(C(C(C(O2)CO)OP(=O)(O)O)OC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCCC)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC)O)O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceSynthetic
Role of LigandNA
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Dogs
Localizationdendritic cells and macrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorF1PDB9.fasta
Swiss prot IDF1PDB9
Length Of Receptor833
Function1,000-fold less toxic than LPS and can be used as vaccines
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay