Detailed description page of PRRDB2.0
| This page displays user query in tabular form. |
PRRID_0684 details |
| Primary information | |
|---|---|
| PRRID | PRRID_0684 |
| Ligand Name | MOMP |
| Source | Shigella flexneri (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It stimulates macrophages, up regulates the surface expression of MHC-II and B7-1 and enhances the production of different cytokines (such as ILp70, TNF-⍺, Il-6) and chemokines (like MIP-1⍺, MIP-1β and RANTES) |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macropahes |
| Domain | LRR |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | It initiates event in the antibacterial host response. |
| Assay used | ELISA |
| PMID | 20347487 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |
| Primary information | |
|---|---|
| PRRID | PRRID_0684 |
| Ligand Name | MOMP |
| Source | Shigella flexneri (Bacteria) |
| Sequence of ligand | NA |
| Length | NA |
| Type | Protein |
| Occurence | Natural |
| Role of Ligand | It stimulates macrophages, up regulates the surface expression of MHC-II and B7-1 and enhances the production of different cytokines (such as ILp70, TNF-⍺, Il-6) and chemokines (like MIP-1⍺, MIP-1β and RANTES) |
| Name of receptor | Toll-like receptor 2 (TLR2) |
| Type of receptor | Toll-like receptor (TLR) |
| Source | Mice |
| Localization | Macropahes |
| Domain | LRR |
| Sequence of Receptor | Q9QUN7.fasta |
| Swiss prot ID | Q9QUN7 |
| Length Of Receptor | 784 |
| Function | It initiates event in the antibacterial host response. |
| Assay used | ELISA |
| PMID | 20347487 |
| Year of Publication | 2010 |
| Pubchem assay | Pubchem Assay |