Detailed description page of PRRDB2.0

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PRRID_0666 details
Primary information
PRRIDPRRID_0666
Ligand NameLpqH
SourceMtb H37Ra (Bacteria)
Sequence of ligandMKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
Length159
TypeLipoprotein
OccurenceNatural
Role of LigandIt activate antibacterial autophagy through vitamin D receptor signalling activation and cathelicidin induction.
Name of receptorcluster of differentiation 14 (CD14)
Type of receptorPattern recognition receptor (PRR)
Source Human
LocalizationPrimary Monocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorP08571.fasta
Swiss prot IDP08571
Length Of Receptor375
FunctionIt leads to the clearance of the pathogen via autophagy
Assay usedNA
PMID20560977
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0666
Ligand NameLpqH
SourceMtb H37Ra (Bacteria)
Sequence of ligandMKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
Length159
TypeLipoprotein
OccurenceNatural
Role of LigandIt activate antibacterial autophagy through vitamin D receptor signalling activation and cathelicidin induction.
Name of receptorcluster of differentiation 14 (CD14)
Type of receptorPattern recognition receptor (PRR)
Source Human
LocalizationPrimary Monocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorP08571.fasta
Swiss prot IDP08571
Length Of Receptor375
FunctionIt leads to the clearance of the pathogen via autophagy
Assay usedNA
PMID20560977
Year of Publication2010
Pubchem assayPubchem Assay