Detailed description page of PRRDB2.0

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PRRID_0664 details
Primary information
PRRIDPRRID_0664
Ligand NameLpqH
SourceMtb H37Ra (Bacteria)
Sequence of ligandMKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
Length159
TypeLipoprotein
OccurenceNatural
Role of LigandIt activate antibacterial autophagy through vitamin D receptor signalling activation and cathelicidin induction.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationPrimary Monocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt leads to the clearance of the pathogen via autophagy
Assay usedNA
PMID20560977
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0664
Ligand NameLpqH
SourceMtb H37Ra (Bacteria)
Sequence of ligandMKRGLTVAVAGAAILVAGLSGCSSNKSTTGSGETTTAAGTTASPGAASGPKVVIDGKDQNVTGSVVCTTAAGNVNIAIGGAATGIAAVLTDGNPPEVKSVGLGNVNGVTLGYTSGTGQGNASATKDGSHYKITGTATGVDMANPMSPVNKSFEIEVTCS
Length159
TypeLipoprotein
OccurenceNatural
Role of LigandIt activate antibacterial autophagy through vitamin D receptor signalling activation and cathelicidin induction.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationPrimary Monocytes
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60603.fasta
Swiss prot IDO60603
Length Of Receptor784
FunctionIt leads to the clearance of the pathogen via autophagy
Assay usedNA
PMID20560977
Year of Publication2010
Pubchem assayPubchem Assay