Detailed description page of PRRDB2.0

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PRRID_0645 details
Primary information
PRRIDPRRID_0645
Ligand NameLipopolysaccharide (LPS)
SourceAspergillus fumigatus(fungi)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandIt induces the secretion of IL-6, IL-8, CC chemokine-ligand 20 (CCL20) and thymosin β4 (Tβ4).
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationTelomerase-Immortalized Human Stroma Fibroblasts (THSFs)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt has the immunostimulatory role.
Assay usedELISA
PMID20305039
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0645
Ligand NameLipopolysaccharide (LPS)
SourceAspergillus fumigatus(fungi)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandIt induces the secretion of IL-6, IL-8, CC chemokine-ligand 20 (CCL20) and thymosin β4 (Tβ4).
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationTelomerase-Immortalized Human Stroma Fibroblasts (THSFs)
DomainNA
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt has the immunostimulatory role.
Assay usedELISA
PMID20305039
Year of Publication2010
Pubchem assayPubchem Assay