Detailed description page of PRRDB2.0

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PRRID_0636 details
Primary information
PRRIDPRRID_0636
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandThe binding results into secretion of low amounts of IL-12(p70) and high levels of IL-10 ompared with adult cells
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCord blood cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionNA
Assay usedNA
PMID20636030
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0636
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandThe binding results into secretion of low amounts of IL-12(p70) and high levels of IL-10 ompared with adult cells
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationCord blood cells
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionNA
Assay usedNA
PMID20636030
Year of Publication2010
Pubchem assayPubchem Assay