Primary information |
---|
PRRID | PRRID_0626 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | NA |
Name of receptor | Toll-like receptor 5 (TLR5) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Microglia |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O60602.fasta |
Swiss prot ID | O60602 |
Length Of Receptor | 858 |
Function | It causes profound microglial activation associated with oligodendrocyte death, demyelination, and increased vulnerability of neurons to injury |
Assay used | NA |
PMID | 20706642 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0626 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | NA |
Name of receptor | Toll-like receptor 5 (TLR5) |
Type of receptor | Toll-like receptor (TLR) |
Source | Human |
Localization | Microglia |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | O60602.fasta |
Swiss prot ID | O60602 |
Length Of Receptor | 858 |
Function | It causes profound microglial activation associated with oligodendrocyte death, demyelination, and increased vulnerability of neurons to injury |
Assay used | NA |
PMID | 20706642 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |