Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0626 details
Primary information
PRRIDPRRID_0626
Ligand NameLipopolysaccharide (LPS)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt causes profound microglial activation associated with oligodendrocyte death, demyelination, and increased vulnerability of neurons to injury
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0626
Ligand NameLipopolysaccharide (LPS)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandNA
Name of receptorToll-like receptor 5 (TLR5)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO60602.fasta
Swiss prot IDO60602
Length Of Receptor858
FunctionIt causes profound microglial activation associated with oligodendrocyte death, demyelination, and increased vulnerability of neurons to injury
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayPubchem Assay