Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0624 details
Primary information
PRRIDPRRID_0624
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandIt produces a large amount of glutamate, an important neurotransmitter but also a potent neurotoxin and is linked to oligodendrocyte injury
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionproduce a large amount of glutamate, an important neurotransmitter but also a potent neurotoxin and is linked to oligodendrocyte injury
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0624
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandIt produces a large amount of glutamate, an important neurotransmitter but also a potent neurotoxin and is linked to oligodendrocyte injury
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationMicroglia
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
Functionproduce a large amount of glutamate, an important neurotransmitter but also a potent neurotoxin and is linked to oligodendrocyte injury
Assay usedNA
PMID20706642
Year of Publication2010
Pubchem assayPubchem Assay