Primary information |
---|
PRRID | PRRID_0621 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Gram-negative bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | induces a signaling cascade that utilizes both the MyD88- and TRIF-dependent pathways, leading to NF-kB and IRF3/7 activation |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice (Murine) |
Localization | dendritic cells and macrophages |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | It has the role in the inflammation. |
Assay used | NA |
PMID | 20713100 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |
Primary information |
---|
PRRID | PRRID_0621 |
Ligand Name | Lipopolysaccharide (LPS) |
Source | Gram-negative bacteria |
Sequence of ligand | CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC |
Length | NA |
Type | Lipopolysaccharide (LPS) |
Occurence | Natural |
Role of Ligand | induces a signaling cascade that utilizes both the MyD88- and TRIF-dependent pathways, leading to NF-kB and IRF3/7 activation |
Name of receptor | Toll-like receptor 4 (TLR4) |
Type of receptor | Toll-like receptor (TLR) |
Source | Mice (Murine) |
Localization | dendritic cells and macrophages |
Domain | Leucine-rich Repeat (LRR) Domain |
Sequence of Receptor | Q9QUK6.fasta |
Swiss prot ID | Q9QUK6 |
Length Of Receptor | 835 |
Function | It has the role in the inflammation. |
Assay used | NA |
PMID | 20713100 |
Year of Publication | 2010 |
Pubchem assay | Pubchem Assay |