Detailed description page of PRRDB2.0

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PRRID_0621 details
Primary information
PRRIDPRRID_0621
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of Ligandinduces a signaling cascade that utilizes both the MyD88- and TRIF-dependent pathways, leading to NF-kB and IRF3/7 activation
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
Localizationdendritic cells and macrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0621
Ligand NameLipopolysaccharide (LPS)
SourceGram-negative bacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of Ligandinduces a signaling cascade that utilizes both the MyD88- and TRIF-dependent pathways, leading to NF-kB and IRF3/7 activation
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Mice (Murine)
Localizationdendritic cells and macrophages
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20713100
Year of Publication2010
Pubchem assayPubchem Assay