Detailed description page of PRRDB2.0

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PRRID_0614 details
Primary information
PRRIDPRRID_0614
Ligand NameLipopolysaccharide (LPS)
SourceS. aureus (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandLipopolysaccharides are the potent activators of TLR4
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source C57BL/6 Mice
LocalizationMacropahges
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionContributes to inflammatory responses induced by orthopaedic wear particles in cell culture and murine models of aseptic loosening of orthopaedic implants
Assay usedNA
PMID20729214
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0614
Ligand NameLipopolysaccharide (LPS)
SourceS. aureus (Bacteria)
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandLipopolysaccharides are the potent activators of TLR4
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source C57BL/6 Mice
LocalizationMacropahges
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUK6.fasta
Swiss prot IDQ9QUK6
Length Of Receptor835
FunctionContributes to inflammatory responses induced by orthopaedic wear particles in cell culture and murine models of aseptic loosening of orthopaedic implants
Assay usedNA
PMID20729214
Year of Publication2010
Pubchem assayPubchem Assay