Detailed description page of PRRDB2.0

This page displays user query in tabular form.

PRRID_0611 details
Primary information
PRRIDPRRID_0611
Ligand NameLipopolysaccharide (LPS)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandActivates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt coauses the inflammation
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0611
Ligand NameLipopolysaccharide (LPS)
SourceBacteria
Sequence of ligandCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC
LengthNA
TypeLipopolysaccharide (LPS)
OccurenceNatural
Role of LigandActivates NF-KB and MAPK which lead to the production of cytokines as TNF and other proinflammatory proteins
Name of receptorToll-like receptor 4 (TLR4)
Type of receptorToll-like receptor (TLR)
Source Human
LocalizationNA
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorO00206.fasta
Swiss prot IDO00206
Length Of Receptor839
FunctionIt coauses the inflammation
Assay usedNA
PMID20740341
Year of Publication2010
Pubchem assayPubchem Assay