Detailed description page of PRRDB2.0

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PRRID_0601 details
Primary information
PRRIDPRRID_0601
Ligand NameLAM
SourceMycobacteria (Bacteria)
Sequence of ligandOC[C@H]1O[C@@H](S[C@H]2[C@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@H](O)[C@@H](CO)O[C@H](Oc4ccc(cc4)[N+]([O-])=O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandIncreases expression of macrophage inflammatory protein-2 , cytokine migration inhibitory factor (MIF), and TNF-α and induces augment PMN migration.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationLung's endothelial cell
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20706658
Year of Publication2010
Pubchem assayPubchem Assay
Primary information
PRRIDPRRID_0601
Ligand NameLAM
SourceMycobacteria (Bacteria)
Sequence of ligandOC[C@H]1O[C@@H](S[C@H]2[C@H](O)[C@@H](CO)O[C@@H](O[C@@H]3[C@H](O)[C@@H](CO)O[C@H](Oc4ccc(cc4)[N+]([O-])=O)[C@@H]3O)[C@@H]2O)[C@H](O)[C@@H](O)[C@@H]1O
LengthNA
TypePattern-associated molecular patterns (PAMPs)
OccurenceNatural
Role of LigandIncreases expression of macrophage inflammatory protein-2 , cytokine migration inhibitory factor (MIF), and TNF-α and induces augment PMN migration.
Name of receptorToll-like receptor 2 (TLR2)
Type of receptorToll-like receptor (TLR)
Source Mice
LocalizationLung's endothelial cell
DomainLeucine-rich Repeat (LRR) Domain
Sequence of ReceptorQ9QUN7.fasta
Swiss prot IDQ9QUN7
Length Of Receptor784
FunctionIt has the role in the inflammation.
Assay usedNA
PMID20706658
Year of Publication2010
Pubchem assayPubchem Assay